Best Business Practices Essay

Best practices is referred to as the development and implementation of a standard way of doing things to improve productivity. New management of business requires the managers and supervisors to be prepared for change. Management skills is not the only task that is expected of these firms but multitasking and flexibility are key to keeping on in today’s fast-paced work environment where experienced supervisors are required. To effectively carry out a number of activities the supervisors of companies need to have a number of best practices required of them. These include good communication skills, determining effective orientation and training methods, improving team productivity, conducting performance appraisals, resolving conflict and improving employee relations. Best practices provide the supervisors with guidelines to follow in ensuring that all the information to be passed is very much effective. Supervisors generally have a difficult task to ensure that all issues are implemented. Therefore they need to utilize the following best practices to ensure that they maintain a successful and productive relationship with employees. Communication skills The supervisors of companies should ensure that the information that is communicated to the organization members is full, accurate, timely and understandable. This policy of good communication applies to different people and groups such as government authorities,’ regulators, employees, clients and the media. In business culture accountability is more important than diplomacy especially in U. S. The supervisors are also expected to do correction and pass judgment criticism in the way businesses are carried. The organization members should not take it as a personal issues but should be taken as away of improving performance in businesses. When correcting the employees the supervisors are expected to treat his employees well not only in pay and benefits but by respecting them and also treating then with a lot of personal care. Correction should be done with the utmost respect and the supervisor is expected to be alone when making correction. (Rue &Byars,2004). In every organization, employees comprise of different members with different cultural differences. This means that the supervisor has to cater for these differences when communicating to his employees. The cultural differences include culture, beliefs value and practices of the organization members. When communicating with the employees the culture should be put into consideration. Communication is just beyond words. The worst thing most supervisors make is failing to implement and demonstrate what they are preaching. For example a supervisor of a company might promise the workers of increase in salary at the end of the month but in the long run he might fail to implement this. This will make the workers or employees to lose trust and faith in their supervisors. The supervisor is thus expected to lead by example. This means taking your employees to the right direction where the firm should be. To stay competitive, companies must find ways to improve the performance and efficiency of all their employees and other members in the new environment inorder to prevent the new and unique challenges in the organization. Crossing the language bridge is another thing that the supervisor should have in mind. This is the biggest issue that supervisors should be aware of. In US, most company workers comprise of people from different cultural background, speaking different languages that all the employees are expected to know. The most commonly spoken language is English. The supervisor of the new company should therefore try to communicate in a language that is familiar and common to everybody. Things will automatically be easier if communication is done in English. However, when passing the information, the language used should be as simple as possible to avoid any complications that might arise. The supervisor should not use a lot of jargons when communicating because this will make the information to be passed to become more difficult to be understood by the employee. The risk of miscommunication will lead to decreased productivity therefore the supervisor should be aware of the language differences in their employees. New concepts should be communicated directly and accurately to the employees in time. It is always said that information liberates when passed at the right time. The channel which the information or message is to follow should be smooth to ensure that the massage passed is not interfered with. New changes should be introduced after effective communications has been done. The new concept introduced should aim at increasing profits and productivity in the company. The supervisor should inform the member on the benefits the new change is going to bring the company. The introduction of the new technology has brought a lot of changes in the business environment. Therefore the organization also needs to change in order to address these changes and stay competitive to the market. Critical thinking also plays a large part of communication especially when communicating with employees. Critical thinking entails asking and answering questions in order to use a thought process that is more easily or effectively remembered. (Rue, 2004) Determining effective orientation and training methods. All organization members need training to acquire new skills and knowledge required for the production to be increased and effective. The supervisor is supposed to hire qualified and competence staff to perform duties in their areas of specialization. Training should provide essential information on the department/programme. This includes policies and procedures on how the organization is run. If the company uses new technology, the supervisor needs to train the employees on how to use the computer soft ware in the company. The supervisor should also provide direction on how work is to be done. He should lead by example and he should also provide appropriate equipment in good working condition and training in how to use it. The supervisor should also do assessment tests to measure effectiveness of training equipment to be used in delivering the training. Methods of training may include use of computer, video, classroom or holding conference. When using these methods the supervisor needs to do assessment first to ensure effective training. Qualified staff needs to be recruited in a specific department. This is because each department has a specific responsibility to be carried. For example a company may have the department of public relations and department of information technology. Those working in the department of information technology need to have relevant skills in the computer database. Improving productivity for teams Team work has become a big part of today’s workforce. Productivity in team can be done through delegation and follow up for example in delegation the supervisors should be well informed about their team members. This should include their cultural background and experiences very well to help him in assigning the right duty to a proper person. By ensuring that delegation is done fairly will provide a positive work team is got which in turn will lead to increased productivity. The supervisor need to know the project he is dealing with and people in the team to find a suitable task for each member. While doing delegation, fairness should be observed as this will keep team morals. Team work productivity is also brought through follow up. This is supposed to be done to ensure that each team member is performing the task that is assigned to him or her. The supervisor therefore needs to check the job done by team members at individual levels and as a team. Follow up will ensure that each member feels satisfied, important and is performing his/her tasks effectively. These actions will help in ensuring that the morals of the team is kept high and therefore leading to happiness in the organization. Conflict resolution. Resolving conflict is another best practice expected of new supervisors. Conflicts are things that normally occur in our organizations. For example our workforce or workplace comprise of people with different cultural background, therefore such diverse cultures can bring conflict in the organization. Conflict that the supervisors therefore mostly faces vary from personality differences between employees to a small clash in attitude or belief. Dealing with conflict requires two things. These include listening and resolving. The supervisor needs to investigate the situation and actively listen to both sides of the situation. The means that he needs to listen to different people involved in the conflict. Listening to a problem requires the supervisors to take time and ensure that each employee has been given an opportunity to speak about the problem (Scenario). While listening, he should carefully take notes and carefully cross check the statements the parties involved are giving. This will enable him understand the root cause of the problem and possible solution to the problem. When coming up with resolution he should determine the one that will appease as many of the population as possible without going against the company policies or regulations (Brett, Behfar & Kern, 2006). All the information in the resolution should be communicated to the employees in a simple way. Follow up should also be done on the situation to confirm whether the resolution that was passed has worked or not. Should it fail to work then another possible solution need to be obtained to resolve the conflict. This will ensure that the whole process of conflict resolution is very successful. Improving employee relations. Improving employee relations is one of the best practices that the supervisor need to have in mind. In most organizations employees will want their presence to be recognized either by their leaders or by other members in the company. Good relationship should therefore be built to ensure that there is a positive contact between the supervisors and other company’s members. (McConnell, 2002). The supervisor should ensure that positive contact is made almost on a daily basis as this will increase the employees self esteem. They will feel that their interest is catered for thereby improving productivity. The supervisor can also create good relations with other members through carrying out regular meetings. During regular meeting the supervisors should address the employee’s problems and correct any area in which they need to improve on. It is also important to keep some records of attendance so that the supervisor can appraise to congratulate them for turning in large numbers. Anyway these minor things need not to be ignored by the supervisors. During meetings it is good and healthy to listen to employees decisions. This is because the employees themselves know where there is need for improvement since they are people carrying out the activities. They therefore know very well where specific improvement is to be made. This makes them feel that they are important in the organization. Even the supervisor himself will feel that he is working to the right direction of achieving the organizations objectives and goals. Improving the employees self esteem will also increase the efficiency and productivity of work done. (Robertson, 2007). The employees therefore should be allowed to take part in decision making process as this will build trust between the employees and their leaders including the supervisors. Performance Appraisal. Conducting performance appraisal is another best practice that the supervisors should not leave out. Performance appraisal is a gauging tool to measure the success and failure in the work done by both the supervisors and employees. In most cases performance appraisal is done yearly basis and include things like reinforcement and giving both positives and negative feed back. Positive feedback is given when the employee does an impressing job. The feedback should begin with positive accomplishment that the employees has since their last appraisal or since they were recruited. The positive not will ensure that the employees follow further direction given by supervisors. Positive feedback will also send a message to the employees that their supervisor is working with them meaning that they are not left alone to o the job without their supervision from their supervisors. This will increase their morale in performing their job. Negative feedback will provide failures that the employees have made and when this is communicated it will help them in making some adjustments. The negative feedback should be used as a teaching tool to guide and correct the employees on the areas they have failed in. These areas therefore need some improvement. If the failures are not communicated to the employees, they won’t know whether they are doing the right thing or the wrong thing. After giving direction on areas that need improvement the supervisor should be clear and concise in the measures that will be taken if a change or improvement is not shown. He will therefore have to check on the ways the task is performed looking into the improvements required or lack of it. When doing this he should continue giving guidance ion hoe the performance can be improved. (Buhler,2007) During performance appraisal the supervisor should give the employees time to ask questions and give their suggestion. This will make them understand more the area in which improvement is required to be done. The supervisors will also be able to know how the employees view the areas he is addressing. However, performance appraisal whether negative or positive feed back should end on a positive note. For example, this is a good work but you still need some improvement. The feedback should contain some goals that the employees need to meet within a stipulated period of time in the near future if the supervisor does the appraisal of performance in a good way then he will realize that his efforts are not thwarted. This will in turn ensure that there is efficiency among the employees and the overall production will increase. Conclusion Every organization needs to employ the principle of best practices to ensure that its goal is achieved. This means that the supervisor will need to consider all the elements making the organization for him to realize success in the company. He needs to work in collaboration with the members as a team and even with the managers to ensure that the policies passed are implemented properly. Keeping the members on toes should be done regularly to ensure that work is done smoothly. A supervisor therefore needs to work in a more professional in the way he handles his employees as this will determine whether job will effectively be done or will not be done. All activities that are to be done particular time should be completed as stated. This will only work upon supervision. The job is only left for the supervisor. Correction should be done in a fair way to avoid any problem arising. This can only be done by using best practices that is used in improving production in a company. The best practice has proved to work and has lead to creation of successful workforce and therefore increased productivity by the company. Reference: Brett, J, Behfar, K & Kern, M. C. (2006). Managing multicultural Teams. London: Harvard Business. Buhler, P. (2007) Managing in the new millennium, Journal of supervision, 68(3) 19-21 Mc Connell, C. (2002) Use positive contacts to improve employee relations. Retrieved July 20, 2007 http://www. nfib. com/object/3174032. htm/ Robertson, J. (2007). How to improve employee’s relations in the workplace. Retrieved July, 19, 2007 http://www. associatedcontent. com/article/17641/low-to-improve-employee-relations-in. htm/ Rue, L. W. & Byars, LL. (2004) Supervision: Key link to productivity: New York: Mc Graw-Hill

Improved More Efficient And Affordable Health Care Health Care Essay

The altering life style of society, an ageing population and the high outlooks for a better quality of life call for improved, more efficient and low-cost wellness attention ( 1 ) . Use of nanotechnology in regenerative medical specialty can offer new intervention modes, when applied to major medical challenges ( 2 ) . Regenerative medical specialty is the method of making life and functional tissues to mend or replace tissue or organ map lost due to inborn defects, harm, disease, or age ( 3 ) . This field holds promise for renewing damaged tissues and variety meats in the organic structure by exciting antecedently irreparable variety meats to mend per se ( 4 ) . Regenerative medical specialty besides permits scientists to turn tissues and variety meats in the research lab and to safely engraft them when the organic structure can non mend itself ( 4 ) . Most significantly, regenerative medical specialty has the possible to work out the job of the deficit of variety meats available fo r life-saving organ organ transplant ( 5 ; 6 ) . Regenerative medical specialty has become a multidisciplinary field ( 7 ) . Application of nanotechnology in regenerative medical specialty can radically alter the manner some diseases are treated in the hereafter. In the last few decennaries, nanomedicines have started coming onto the market ( 8 ) . Regenerative medical specialty can be used to reconstruct, keep or heighten tissues and therefore organ maps. Regeneration of tissues can be achieved by the combination of life cells, which will supply biological functionality, and stuffs, which act as scaffolds to back up cell proliferation ( 8 ; 7 ; 9 ) . In vivo mammalian cells respond to the biological signals they receive from the environing environment. These signals are controlled by nanometer-scaled constituents, so it is really of import that the stuff used produces the right signal to steer cell growing and functionality suitably ( 10 ) . The application of nanotechnology to regenerative medical specialty is a broad country ( 1 1 ) . Nanotechnology is an first-class tool for bring forthing scaffolds that mimic the biological constructions. This engineering besides offers efficient drug bringing system. In this survey, we focused on three different applications of regenerative medical specialty. Our first purpose was to develop an anodization technique to bring forth surface modified nanoporous Ti that can be used as possible system for technology a typical biomaterial for bone tissue technology. Our 2nd purpose was to manufacture a halloysite-PCL ( poly--caprolactone ) scaffold and measure its ability to back up cell growing, distinction, and fucntionality. The concluding purpose was to analyze the consequence of different drug loaded halloysite-PCL scaffold as possible bactericide, antiseptic and bactericidal stuff.Nanoparticles and Nanotubes for Regenerative MedicineExtensive libraries of nanoparticles, composed of an mixture of different sizes, forms, and stuffs, and with assorted chemical and surface belongingss, have already been constructed. The field ofA nanotechnologyA is under changeless and rapid growing and new add-ons continue to supplement these libraries. Examples of nanoparticles are buckminsterfullerenes, liquid crystals, liposomes, nanoshells, quantum points and supramegnetic nanoparticles. Carbon nanotubes and halloysite nanotubes are illustration of nanotubes. Liquid Crystals Liquid crystal pharmaceuticals are composed of organic liquid crystal stuffs that mimic naturally-occuring biomolecules like proteins or lipoids. They are considered a really safe method for drug bringing and can aim specific countries of the organic structure where tissues are inflamed, or where tumours are found. Liposomes Liposomes are lipid-basedA liquid crystals, used extensively in the pharmaceutical and decorative industries because of their capacity for interrupting down indoors cells one time their bringing map has been met. Liposomes were the first engineered nanoparticles used for drug bringing but jobs such as their leaning to blend together in aqueous environments and warhead release, have led to replacement, or stabilisation utilizing newer alternate nanoparticles. Nanoshells Besides referred to as core-shells, nanoshells are spherical nucleuss of a peculiar compound surrounded by a shell or outer coating of another, which is a few nanometres in thickness. Quantum points Besides known as nanocrystals, quantum points are nanosized semiconducting materials that, depending on their size, can breathe light in all colourss of the rainbow. These nanostructures confine conductivity set negatrons, valency set holes, or excitons in all three spatial waies. Examples of quantum points are semiconductor nanocrystals and core-shell nanocrystals, where there is an interface between different semiconducting material stuffs. They have been applied in biotechnology for cell labeling and imagination, peculiarly in malignant neoplastic disease imagination surveies. Superparamagnetic nanoparticles Superparamagnetic molecules are those that are attracted to a magnetic field but do non retain residuary magnetic attraction after the field is removed. Nanoparticles of Fe oxide with diameters in the 5-100 nanometer scope, have been used for selective magnetic bioseparations. Typical techniques involve surfacing the atoms with antibodies to cell-specific antigens, for separation from the environing matrix. Used in membrane conveyance surveies, superparamagenetic Fe oxide nanoparticles ( SPION ) are applied for drug bringing and cistron transfection. Targeted bringing of drugs, bioactive molecules or Deoxyribonucleic acid vectors is dependent on the application of an external magnetic force that accelerates and directs their advancement towards the mark tissue. They are besides utile as MRI contrast agents. Dendrimers Dendrimers are extremely branched constructions deriving broad usage in nanomedicine because of the multiple molecular â€Å" maulerss † on their surfaces that can be used to attach cell-identification tickets, fluorescent dyes, enzymes and other molecules. The first dendritic molecules were produced around 1980, but involvement in them has blossomed more late as their biotechnological utilizations were discovered.Carbon nanotubesTypically 1-100 nanometer in length, nanotubes are most frequently made from semiconducting stuffs and used in nanomedicine as imagination and contrast agents. Nanotubes can be made by bring forthing little cylinders of Si, gold or inorganic phosphate, among other stuffs.Carbon nanotubesNanosized tubings of C known as C nanotubes possess optical passages in the near-infrared that can be utilized for tracking cells. The infrared spectrum between 900 and 1,300nm is an of import optical window for biomedical applications because of the lower optical wind ow for biomedical applications because of the lower optical soaking up and little auto-fluorescent background. Like QD, C nanotubes possess good photostabillity and can be imaged over long periods of clip utilizing Raman sprinkling and fluorescence microscopy. However, unlike QD, which are typically composed of heavy metals such as Cd, C nanotubes are made of C, an abundant component in nature. Carbon nanotubes possess big aspect ratios with nanometer diameters and length runing from submicron to millimetres. These tubings can incorporate a individual wall of C ( SWNT ) or multiple walls of C nanotubes ( MWNT ) . The little size of the SWNT makes it possible for 70,000 nanotubes to be ingested where they can stay stable for hebdomads indoors 3T3 fibroblasts and murine myoblast root cells. Having such a high concentration of C nanotubes within a cell distinction, even though. While such nanomaterials have yet to make clinical application, it does demo the possible for non-invasive op tical imagination.Nanomodified SurfacesAn ideal scaffold for tissue regeneration should hold similarity to native excess cellular matrices in footings of both chemical composing and physical nanostructure. Recently, nanostructured biomaterials holding physical nanofeatures such as nanocrystals, nanofibers nanosurfaces, nanocomposites, etc. gained much involvement in regenerative medical specialty. This is chiefly because of their resemblance of physical nanofeatures to natural ECM. There are many different type of scaffold: nanocrystalline bioresorbable bioceramic scaffolds and nanofibrous polymeric scaffolds for tissue regeneration. Fabrication of porous bioceramics based on HA and other Ca phosphates with interrelated pore construction can be done by the reproduction of polymer froth. The advantage of this technique is the control over porousness, pore geometry and pore size of the fancied scaffolds. Electrospinning is a versatile technique to manufacture nanofibrous polymeric mat rices for usage in regenerative medical specialty. The recent developments in electrospun scaffolds with a particular accent on FDA approved biodegradable polymers such as PCL, PLA, PLGA, collagens, etc have been extensively studied. Particular attending has been given to the mechanical belongingss and cell interaction of the electrospun fibre mats. Electrostatic cospinning of polymers with nanohydroxyapatite to manufacture intercrossed nanocomposite scaffolds as possible scaffolds miming the complex nanostructured architecture of bone has been suggested for difficult tissue regeneration. Advanced techniques for the readying of nanofibers, nucleus shell fibres, hollow fibres, and rods and tubings from natural and man-made polymers with diameters down to a few nanometres have late been established. These techniques, among them electro- and coelectrospinning and specific templet methods, let the incorporation non merely of semiconducting material or catalytic nanoparticles or chromophores but besides enzymes, proteins, micro-organism, etc. , straight during the readying procedure into these nanostructures in a really soft manner. One peculiar advantage is that biological objects such as, for case, proteins can be immobilized in a fluid environment within these polymer-based nano-objects in such a manner that they keep their native conformation and the corresponding maps. The scope of applications of such biohybrid nanosystems is highly wide, for case, in the countries of biosensors, contact action, drug bringing, or optoelectronic Nanostructures promote formation of blood vass ; bolster cardiovascular map after bosom onslaught – Injecting nanoparticles into the Black Marias of mice that suffered bosom onslaughts helped reconstruct cardiovascular map in these animate beings. The self-assembling nanoparticles – made from of course happening polyoses and molecules known as peptide amphiphiles – encouragement chemical signals to nearby cells that induce formation of new blood vass and this may be the mechanism through which they restore cardiovascular map. One month subsequently, the Black Marias of the treated mice were capable of undertaking and pumping blood about every bit good as healthy mice. In contrast, the Black Marias of untreated mice contracted about 50 per centum less than normal. In other recent surveies utilizing a similar technique, Stupp and his co-workers found nanoparticles hastened wound mending in coneies and, after islet organ transplant, cured diabetes in mice. Nanoparti cles with other chemical composings accelerate bone fix in rats and advance the growing of nerve cells in mice and rats with spinal cord hurts. The recent progresss in the readying of some nanomaterials, turning consciousness of stuff scientific discipline and tissue technology research workers sing the potency of root cells for regenerative medical specialty, and progresss in root cell biological science have contributed towards the encouragement of this research field in the last few old ages. Nanoparticles have several possible applications such as intracellular drug bearers to command root cell distinction and biosensors to supervise in existent clip the intracellular degrees of relevant biomolecules/enzymes. Cell-based therapies have produced important enthusiasm and survey and are one of the most active countries of research in regenerative medical specialty. The creative activity of multi-functional tools, which allow the improved monitoring and modifying of cell behaviour is one method of speed uping the gait of research. While cell-based a therapy in malignant neoplastic disease is a immense portion of the nanomedicine attempt for regenerative medical specialty. Bettering non-invasive monitoring methods is peculiarly desirable since current methods of measuring cell intervention typically affect destructive or invasive techniques such as tissue biopsies. Traditional non-invasive methods such as magnetic resonance imagination ( MRI ) and positron emanation imaging ( PET ) , which rely to a great extent on contrast agents, lack the specificity or resident clip to be a feasible option for cell trailing. However, in vitro and in vivo visual image of nanoscale systems can be carried out u tilizing a assortment of clinically relevant modes such as fluoresce microscopy, individual photon emanation computed imaging ( SPECT ) , PET, MRI, ultrasound, and radiotracing such as gamma scintigraphy. Nanoparticulate imaging investigations include semi-conductor quantum points ( QD ) , magnetic and magnetofluorescent nanoparticles, gold nanoparticles, and nanoshells among others, While there are presently few illustrations of nanotechnologies being applied to the apprehension of of import procedure in tissue regeneration, relevant utilizations of nanoparticles for regenerative medical specialty such as monitoring angiogensis and programmed cell death are looking.Tissue Engineering in Dental and OrthopedicPractice Implications.AIt is predicted that tissue technology will hold a considerableA consequence on dental pattern during the following 25 old ages. The greatestA effects will probably be related to the fix and replacementA of mineralized tissues, the publicity of unwritten l esion healingA and the usage of cistron transportation adjunctively. Tissue technology buildsA on the interface between stuffs scientific discipline and biocompatibility, A and integrates cells, natural or man-made scaffolds, and specificA signals to make new tissues.A This field is progressively beingA viewed as holding tremendous clinical potency. Clinical jobs associating to the loss and/or failure of tissuesA extend beyond dental medicine to all Fieldss of medical specialty, and are estimatedA to account for about one-half of all medical-relatedA jobs in the United States each twelvemonth. Currently, the replacementA of lost or lacking tissues involves prosthetic stuffs, A drug therapies, and tissue and organ organ transplant. However, A all of these have restrictions, including the inability of syntheticA prosthetic devices to replace any but the simplest structural functionsA of a tissue. An utmost deficit of variety meats and tissues for transplantationA exists. Fewer than 10,000 variety meats are available for transplantationA each twelvemonth in the United States, while more than 50,000 patientsA are registered on organ transplant waiting lists.A Such problemsA have motivated the development of tissue technology, whichA can be defined as a â€Å" combination of the rules and methodsA of the life scientific disciplines with those of technology to develop materialsA and methods to mend damaged or morbid tissues, and to createA full tissue replacings. † Many schemes have evolved to engineer new tissues and variety meats, A but virtually all combine a stuff with either bioactive moleculesA that induce weave formation or cells grown in the laboratory.A The bioactive molecules are often growing factor proteinsA that are involved in natural tissue formation and remodeling.A The basic hypothesis underlying this attack is that the localA bringing of an appropriate factor at a correct dosage for a definedA period of clip can take to the enlisting, proliferation andA distinction of a patient ‘s cells from next sites.A These cells can so take part in tissue fix and/or regenerationA at the needed anatomic venue. The 2nd general scheme uses cells grown in the laboratoryA and placed in a matrix at the site where new tissue or organA formation is desired. These transplanted cells normally are derivedA from a little tissue biopsy specimen and have been expanded inA the research lab to let a big organ or tissue mass to be engineered.A Typically, the new tissue will be formed in portion from theseA transplanted cells. With both attacks, specific stuffs deliver the moleculesA or cells to the appropriate anatomic site and supply mechanicalA support to the organizing tissue by moving as a scaffold to guideA new tissue formation.A Currently, most tissue technology effortsA usage biomaterials already approved for medical indicants byA the U.S. Food and Drug Administration, or FDA. The most widelyA used man-made stuffs are polymers of lactide and glycolideA , since these are normally used forA biodegradable suturas. Both polymers have a long path recordA for human usage and are considered biocompatible, and their physicalA belongingss ( for illustration, debasement rate, mechanical strength ) A can be readily manipulated. A natural polymer-type 1 collagen-isA frequently used because of its comparative biocompatibility and abilityA to be remodeled by cells. Other polymers familiar to dentistry, including alginate, are besides being used. Bone and gristle coevals by autogenic cell/tissue organ transplant is one of the most promising techniques in orthopaedic surgery and biomedical technology [ 1 ] . Treatment constructs based on those techniques would extinguish jobs of donor site scarceness, immune rejection and pathogen transportation [ 2 ] . Osteoblasts, chondrocytes and mesenchymal root cells obtained from the patient ‘s difficult and soft tissues can be expanded in civilization and seeded onto a scaffold that will slowly degrade and resorb as the tissue structures grow in vitro and/or vivo [ 3 ] . scaffold or 3-dimensional ( 3-D ) concept provides the necessary support for cells to proliferate and keep their di! erentiated map, and its architecture the ultimate form of the new bone and gristle. Several scaffold stuffs have been investigated for tissue technology bone and gristle including hydroxyapatite ( HA ) , poly ( a-hydroxyesters ) , and natural polymers such as collagen and chitin. Several reappraisals have been published on the general belongingss and design characteristics of biodegradable and bioresorbable polymers and scaffolds [ 4,12 ] . In the United States each twelvemonth, over half a million people undergo entire joint replacing ( 14 ) . The mean lifetime of a rehabilitative articulation implant is about 15 old ages. In all likeliness this means that each patient will hold to undergo a 2nd surgery to keep functionality ( 15 ) . There are many drawbacks with replacing surgeries such as inferior recovery compared to the initial surgery, postsurgical complications and hurting ( 16 ) . The most common account for implant failure is improper growing on the implant surface ( 17 ) . Currently V, Co, Cr and smooth Ti are used in dental and orthopaedic implants. Out of all these metals, Ti is most often used due to its tensile strength and corrosion opposition ( 13 ; 18 ; 19 ) . But the job with Ti implants is that it does non mime the natural bone construction. So there are higher opportunities of implant failure ( 20 ) . Natural bone is nanoporous at the surface. So if we modify the surface of Ti such that it becomes na noporus, this may assist in increasing the life span of the implant. So the first aim is to bring forth nanoporus Ti by the procedure of anodization.Nanotechnology for Bioactive Molecule and Drug ReleaseControlled drug bringing is one of the most promising biomedical applications of nanotechnology. The usage of nanomaterials as nanocarriers for bettering bringing methods has shown to be advantageous technically and feasible economically. Controlled release of antibiotics and antiseptic drug from halloysite PCL scaffold can be used for lesion healing. The basic unit of mending in any tissue type ( for illustration bone or tegument ) is the same. The 2nd nonsubjective, of this undertaking is to electrospin PCL-halloysite scaffold, happen the best concentration and the exact location of halloysite in the PCL-halloysite scaffold by Fluorescein isothiocyanateA ( FITC ) labeling of halloysite and look into its biocompatibility. The 3rd aim of this undertaking is to bring forth drug loaded halloysite-PCL scaffold and trial it effectiveness on bacteriums.Undertaking Aim1. To happen out the best parametric quantity of anodization to bring forth nanoporous Ti. Compare osteoblast cell proliferation and distinction on smooth versus nanoporous Ti surfaces. Nanoporous surfaces should take to better cell proliferation and distinction taking to heighten implant lastingness and osteointegration for patients with degenerative articulation jobs, as it is similar to natural bone surface. 2. To electro-spin halloysite-PCL scaffold and happen the best concentration and the exact location of halloysite in the halloysite-PCL scaffold by Fluorescein isothiocyanateA ( FITC ) labeling of the halloysite, compare osteoblast cell proliferation and distinction on PCL and halloysite-PCL scaffolds. 3. To lade halloysite nanotubes with drugs, for illustration antibiotics and antiseptic, mensurate the drug released from the halloysite and document the consequence of the drug released from the halloysite-PCL scaffold on bacteriums.

My Antonia and Huckleberry Finn Essay

Characters from various books that may or may not have anything to do with one another can be similar and different in many ways. Huckleberry Finn from The Adventures of Tom Sawyer by Mark Twain, and Antonia Shimerda from My Antonia by Willa Cather are similar in a variety of ways, however they have important differences. Huckleberry Finn is always ready to go on any type of adventure with his best friend Tom Sawyer. Also, the pair are extremely superstitious. Huck is discriminated against for a myriad of reasons. Some being, he is the son of the town drunk, so the adults frown upon him. Because of his father’s lifestyle he is basically an orphan, he has to find his own food, clothes, and a place to sleep. He also does not attend church or school. Opposite to that, the boys of the town envy him for his freedom and lack of discipline. The Widow Douglass who lives in town offers Huck a place to stay. She says he can live in her house, and with the money from the treasure he and Tom found she would be able to support him. Tom encouraged Huck to take advantage of this offer while he could. This was a hard decision for Huck to make because he is not willing to give up his independence that he is accustomed to. He lives with the widow for a short period of time then decides he enjoys being on his own and is willing to face the hardships of life by himself to maintain his freedom. Antonia Shimerda is extremely generous and optimistic. Through the hardships of immigrating to America from Bohemia, her father committing suicide, and her fiance leaving her before they get married, and at this time she is pregnant, she never looses hope. She looks for the best in every situation and tries to find a solution for everything. Everyday she has to face racial and gender discrimination. She is judged brutally by the townspeople because of her love for dance. Her and her family, which now consists of her mother, brothers and sisters, have to face the difficulties of life after the death of their father along with the difficulties of living in a new country. Her and her family are living in poverty, and are trying extremely hard just to survive. Later, Antonia works as a servant. Her boss does not like her habit of attending the dances she enjoys going to. He threatens to fire her if she continues to attend these dances. She loves her independence too much to let someone take it away. So she works for a brutal boss and suffers so she can have her independence and go to her dances. Huckleberry Finn and Antonia Shimerda have many similarities and differences. They have very different characteristics, however they both face many hardships, discrimination on a daily basis, and they both value their independence a lot that they would rather live harder lives so they can be independent.

Management Decision Making Case Study Example | Topics and Well Written Essays - 250 words - 3

Management Decision Making - Case Study Example In arriving at a decision, the team applies to cause and effect diagram, which investigates business systems for possible problems which cause inefficiencies. A decision making chain slows down due to lack of harmony among team members tasked with that responsibility. In the same way, a processing machine slows down hindering the continuous flow of goods in the conveyor belt. The team given this mandate uses cause and effect diagrams to come up with overall facts about the system. The process starts with investigations which look into possible reasons for a particular effect. In this case, the team investigates the Executive Information System (EIS) and finds out that major problems lie in the implementation. This is because the management is not equipped with the right skills required to run the system during the implementation stage. Cause and effect diagrams list from the biggest cause for the problem to the least, to guide the team in prioritizing courses for action (Sproull, 200 1). A Pareto chart is a combination of a line and bar graph, used to bring out the differences in data validity, and highlights the most useful ones. This helps quality assurance managers in testing the system for any faults which affecting business process. For instance, when investigating why ATM cards are taking too long to process at a bank, all ATM application issues are listed in order of frequency to establish where the gap is mostly concentrated. This is where problem-solving commences when addressing system issues. The team used a combination of these tools to come up with the recommendations, which excluded software and hardware components from the EIS implementation issues. In establishing the cause, right decisions are made in singling out the two issues. This two-tier approach is ideal for bringing out the most valid reasons for low uptake of the system. The only problem with this approach is that minor issues might be overlooked with has a potential of causing hitches later on in the system.

Properties of Acetysalicylic Acid Lab Report Example | Topics and Well Written Essays - 3250 words

Properties of Acetysalicylic Acid - Lab Report Example But when both the blue and red –OH groups are replaced, the result is heroin. Morphine is considered as the gold standard of analgesics since it is effective in relieving pain. However, the excessive amount of morphine can depress the respiratory system. Morphine works by blocking receptor sites that signal pain to the brain. The key to morphine’s efficacy is its shape which fits into the cells. Moreover, morphine acts like natural painkillers such as endorphins. - as weak acids, alcohols and phenols dissociate to a slight extent in dilute aqueous solution y donating a proton to water, generating H3O + and alkoxide ion ( RO -) or a phenoxide ion ( A+0 - ) Warfarin is an anticoagulant, meaning, it acts as blood thinner like aspirin. However, warfarin is more potent and can even cause severe hemorrhaging. This is due to the fact that warfarin can decrease coagulation through inhibition of Vitamin K. It is synthetically derived from coumarin, which is extracted from plants such as licorice, lavender, and Woodruff. Warfarin is commonly used in rat pesticide. Once a cat ingests a mouse that ate warfarin-laced pesticide, the cat’s liver would fail and internal bleeding occurs immediately. However, warfarin has also therapeutic purposes especially in the prevention of thrombosis as well as an embolism. To measure: the pH of the aqueous phases is adjusted such that the predominant form of the compound is unionized. The logarithm of the ratio of the concentration of the un-ionized solute is the solvent called log P. The shake flask or tube method is the most classical method known by the chemist. The process is simple: the solute in question is slowly dissolved in a certain volume of octanol and H2O.  

Volcanoes Essay Example | Topics and Well Written Essays - 750 words

Volcanoes - Essay Example Shield Volcano c. Dome Volcano d. Ash-Cinder e. Composite f. Caldera 5. Volcanoes in history and culture ii. disasters type 1 1. Impact on environment, 2. Impact economy 3. Impact people iii. disasters type 2 1. Impact on environment, 2. Impact economy 3. Impact people iv. Solutions proposed by the questions: privatization III. Volcano – Business Opportunities a. Prior eruption i. Geothermal 1. Historical use a. Refuge b. Balenology 2. Common use a. geothermal (ground-source) heat pumps (GHP b. bathing/swimming/spas c. space heating (including district heating d. aquaculture e. agriculture 3. Mechanism a. intrusion of molten rock (magma) b. high surface heat flow c. Heated groundwater 4. Environmental effects a. Emissions b. Noise c. Water use d. Land use e. Impact on natural phenomena, wildlife and vegetation ii. Tourism 1. Types of tourists a. Tours b. Students c. Adventurous 2. Visitors motivations a. Part of the tour, not a specific interests b. Sports c. Photography d. Sc ientific observation 3. The demand for volcano and geothermal tourism 4. Risk management a. Education i. Volcano in it self ii. Emergency actions b. To have qualified guides c. International safety guideline 5. Study case: Galapagos Islands, Volcanoes and wildlife a. Introduction, Location b. Geophysical aspect and history of activity c. Tourism d. Risk factors e. Risk management b. Post eruption i. lava mining 1. Study Case: Merapi Indonesia a. Stone property and use for sculpture b. Advantages ii. Agriculture: fertility of soil 1. Earth Properties 2. Economic impact 3. Study cases iii. Ashes business 1. Product tools 2. Transportation IV. Disasters type 1: tornado, hurricane, tsunami – Business Opportunities a. Domains of need and wants: i. Food ii. shelter iii. utilities iv. financing, v. work force planning vi. housing, security vii. communication and information technology viii. medical ix. transportation x. Insurance V. Disaster type 2: fire and floods – Business Opportunities a. Soil fertility b. Reconstruction VI. Discussion a. Reminding question and hypothesis. i. What are the business opportunities in a volcano ii. That I must be limited because we don’t really hear about it and it is not used much iii. The research about the subject refuted the hypothesis. b. GEOTHERMAL AND FINDINGS i. According to findings geothermal is been used but mostly in Europe and US ii. Why? iii. East African- findings-potential area to exploit iv. Problem developed and developing country and renewable energy c. GEOTOURISM AND FINDINGS i. Unexpected finding. Geotourism is quite developed. d. SOIL FERTILITY AND ASHESAND Findings i. Ashes have many consequences 1. Soil fertility, the nutriments, that is why we find lots of people surrounding volcanic areas 2. Beauty tool 3. Problems related to ashes a. Lava mining b. Explain why it doesn’t figure in the paper 4. Limited relevant work citied a. Depth of the explanation is very high/ engineering leve l b. Potential research VII. Conclusion a. Limitation of the subject b. Not new but not developed concept c. Clear business opportunities i. The impact of these opportunities. How the can influence our world and create a better place Introduction: Natural resources seem to be the epicenter of multiple problems. Different geographical locations on the globe possess different potentials in terms of natural resources. â€Å"Naturally people will tend to exploit areas where they will gain more productivity with minimum investment†

History ( global civilization ) Term Paper Example | Topics and Well Written Essays - 250 words - 1

History ( global civilization ) - Term Paper Example This was the reason for the east and native rebellions for their trade increases. The main reason for the partition of Africa was that in 1882, Britain took it over and in 1890’s it took the biggest share of the east - central Africa, Sudan and Rhodesias. In 1898, there were conflicts with France and Germany. 1n 1900, Europeans led only Ethiopia and Liberia leaving the rest of Africa. The European partitioners thought of Africa as a mirage and cared more about vision rather than reality. In the view of Africans it was unification what Europeans thought as partition. Soon after the partition of Africa, the Europeans started initiating colonization and political units within their societies with diversified history and cultural background. By the end of 19th Century, the Europeans divided the major part of Africa amongst themselves. Finally, the African nationalists took over the artificial units made by Europeans who dominated and exploited Africa (Koponen, pp.